The Apothecary Diaries Season 3 Reveals Second Trailer and Eve Ending Theme

The production committee for The Apothecary Diaries unveiled Season 3's second promotional video on September 25, confirming Eve's new song "AIYOU" as the ending theme. The trailer arrives one week before the series begins its Japanese television broadcast on October 2 at 11 p.m.

What the second trailer reveals

The new preview shifts the story's scope outward while keeping Maomao and Jinshi at its center. Jinshi, now facing the obligations attached to his true status as the imperial brother, confronts rumors about a mysterious immortal woman and a disaster said to threaten the country. Maomao stands beside him as the pair take on the unfolding problem.

The official description says the setting will move from the rear palace into the city and then into a neighboring country. Images of the enigmatic woman, glimpses of the approaching calamity, and Jinshi's growing royal responsibilities frame the season's central mysteries. The preview therefore links the widening investigation to a more personal question about how Jinshi will carry the burden of his position.

The video closes with the emperor considering whether it is time for Jinshi to choose a bride, followed by a subdued line from Jinshi. That sequence places court expectations beside the season's larger danger and emphasizes that his formal return to royal life will affect more than his duties. The production's synopsis also points to possible changes in his relationship with Maomao as they face the new threat together.

Season 3 will air through Nippon TV's Friday Anime Night block across 30 stations in Japan. Episodes are scheduled for Fridays at 11 p.m., and the official site says streaming platforms will begin carrying them sequentially after broadcast.

How Eve's "AIYOU" connects to Jinshi

"AIYOU" is heard in the promotional video, giving viewers their first sample of the ending theme before the premiere. The production describes the song as gentle but tinged with sadness, with its sound intended to accompany Jinshi's feelings as he takes on new responsibilities as the imperial brother.

Eve said the song grew from thinking about emotions that resist easy explanation and the distance that can appear even between two people standing close together. The artist also connected the composition to a desire to see someone beyond the roles and positions imposed on them. Those ideas align directly with the trailer's presentation of Jinshi, whose public identity and private feelings are becoming difficult to separate.

The official announcement introduces the track through the same footage that establishes Jinshi's royal obligations and his bond with Maomao. That pairing makes the ending theme part of the season's emotional setup: the mystery expands beyond the palace, while the two central characters must navigate the pressures created by status, duty, and feelings that remain hard to express.

Season 3 begins broadcasting on October 2 at 11 p.m., making the premiere the next confirmed milestone. The second trailer establishes the immediate questions ahead: what the foretold disaster means, who the mysterious woman is, and how Jinshi's royal obligations will reshape his partnership with Maomao.